The Entourage Effect


What is the Entourage Effect?


When we intake cannabis products we are not only ingesting the THC and CBD, but also the numerous other chemical compounds that we discussed in our last post. These combinations of beneficial compounds working together create a unique effect depending on concentration level and method of intake. This is what we call the “Entourage Effect.”

How to select for the Entourage Effect

For many full time cannabis users this term most likely will not be new, and might even be how you are currently choosing your cannabis products. These unique combinations of cannabis compounds are said to create individualized effects depending on the strain and can differ from grow to grow. We can take CBN as an example. CBN is said to help induce sleep and help with insomnia. Many users who are looking for products specifically for sleep might want to look at other concentration levels other than just the base THC and CBD. Not to say these are not important factors as well.

The Future

Though we have made great progress in recent history on the understanding of these compounds and their physiological effects, we are still only scratching the surface. As advocacy for cannabis research grows stronger and more states start to recreationally, it will be important for users to have access to well run, peer reviewed studies.


Join us next time for more fun facts about cannabis and its many uses!




Customer Safety During COVID-19

Holyoke Cannabis implements a wide range of sanitation and safety measures. Health and security are major priorities for their walk-in customers. “We are constantly sanitizing our sales floor and counterspace and offer both hand sanitizer and masks to all customers.” explains Jacob Black, Marketing and procurement Manager for Holyoke Cannabis. “Customers can also pre-order through our website in order to decrease your time spent in store. We take our customers safety concerns extremely seriously.”.  If you have any questions or concerns, please call 413-322-8611 and a Holyoke Cannabis Bud Tender will have the answer you need.

Products and Education

Due to the previously mentioned influx of cannabis users joining the recreational market, one major goal of Holyoke Cannabis is to properly educate and inform for both its Budtenders and Customers. Holyoke Cannabis provides an extensive product guide that details/describes all major forms of cannabis intake from yummy edibles to old school buds and everything in between. If you are more of a person-to-person learner, the Holyoke Cannabis staff is more than happy to answer all questions in a warm and friendly environment.

Revitalization of Holyoke and Holyoke Cannabis

With so many amazing business’s moving into the beautiful Mill area of 380 Dwight Street, Holyoke Cannabis expects a bright future for economic, infrastructural, and social uplift throughout Holyoke and its surrounding areas. “Holyoke Cannabis is excited to be part of such a driven community of business owners” “We only see things going up from here” remarked Jaron as the sound of new construction rings out from outside.

Location and Access

Access to transportation whether it be long distances, or one town over can be a great concern for customers who wish to partake in cannabis product safely. Holyoke Cannabis and the 380 Dwight St. plaza is located only a short distance from both a train station and local bus stop and is available to all.

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Skip the line using our online menu and checkout at the express pick up window! Menu is updated regularly for your ordering convenience.

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  • “Please Consume Responsibly”
  • “Marijuana can impair concentration, coordination and judgment. Do not
    operate a vehicle or machinery under the influence of this drug.”
  • “For use only by adults 21 years of age or older. Keep out of the reach of
  • “This product has not been analyzed or approved by the Food and Drug Administration
    (FDA). There is limited information on the side effects of using this product, and there
    may be associated health risks. Marijuana use during pregnancy and breast-feeding may
    pose potential harms. It is against the law to drive or operate machinery when under the
    influence of this product. KEEP THIS PRODUCT AWAY FROM CHILDREN. There
    may be health risks associated with consumption of this product. Marijuana can impair
    concentration, coordination, and judgment. The impairment effects of Edibles may be
    delayed by two hours or more. In case of accidental ingestion, contact poison control
    hotline 1-800-222-1222 or 9-1-1. This product may be illegal outside of MA.”
Our Location

380 Dwight St. #3
Holyoke, MA 01040
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phone: (413) 322-8611

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